C# 直到下一次垃圾回收时才释放。但是，如果您没有使用VSTO，您应该能够调用GC.Collect（）和GC.WaitForPendingFinalizers（）一次

我知道显式调用

GC.Collect（）

是不可能的（当然，两次调用听起来非常痛苦），但老实说，没有办法解决这个问题。通过正常操作，您将生成没有引用的隐藏对象，因此，除了调用

GC.Collect（）

，您无法释放这些对象

这是一个复杂的话题，但这真的是它的全部。一旦为清理过程建立了此模板，就可以正常编写代码，而不需要包装器等：-）

我在这里有一个关于这方面的教程：

---

它是为VB.NET编写的，但不要因此而延迟，其原理与使用C#时完全相同。

您需要注意，Excel对您运行的文化也非常敏感

您可能会发现，在调用Excel函数之前，需要将区域性设置为EN-US。 这并不适用于所有函数，但适用于其中一些函数

    CultureInfo en_US = new System.Globalization.CultureInfo("en-US"); 
    System.Threading.Thread.CurrentThread.CurrentCulture = en_US;
    string filePathLocal = _applicationObject.ActiveWorkbook.Path;
    System.Threading.Thread.CurrentThread.CurrentCulture = orgCulture;

即使您正在使用VSTO，这也适用

有关详细信息：

I一个有用的通用模板，可以帮助实现COM对象的正确处理模式，当COM对象超出范围时需要调用Marshal.ReleaseComObject：

用法：

using (AutoReleaseComObject<Application> excelApplicationWrapper = new AutoReleaseComObject<Application>(new Application()))
{
    try
    {
        using (AutoReleaseComObject<Workbook> workbookWrapper = new AutoReleaseComObject<Workbook>(excelApplicationWrapper.ComObject.Workbooks.Open(namedRangeBase.FullName, false, false, missing, missing, missing, true, missing, missing, true, missing, missing, missing, missing, missing)))
        {
           // do something with your workbook....
        }
    }
    finally
    {
         excelApplicationWrapper.ComObject.Quit();
    } 
}

public class AutoReleaseComObject<T> : IDisposable
{
    private T m_comObject;
    private bool m_armed = true;
    private bool m_disposed = false;

    public AutoReleaseComObject(T comObject)
    {
        Debug.Assert(comObject != null);
        m_comObject = comObject;
    }

#if DEBUG
    ~AutoReleaseComObject()
    {
        // We should have been disposed using Dispose().
        Debug.WriteLine("Finalize being called, should have been disposed");

        if (this.ComObject != null)
        {
            Debug.WriteLine(string.Format("ComObject was not null:{0}, name:{1}.", this.ComObject, this.ComObjectName));
        }

        //Debug.Assert(false);
    }
#endif

    public T ComObject
    {
        get
        {
            Debug.Assert(!m_disposed);
            return m_comObject;
        }
    }

    private string ComObjectName
    {
        get
        {
            if(this.ComObject is Microsoft.Office.Interop.Excel.Workbook)
            {
                return ((Microsoft.Office.Interop.Excel.Workbook)this.ComObject).Name;
            }

            return null;
        }
    }

    public void Disarm()
    {
        Debug.Assert(!m_disposed);
        m_armed = false;
    }

    #region IDisposable Members

    public void Dispose()
    {
        Dispose(true);
#if DEBUG
        GC.SuppressFinalize(this);
#endif
    }

    #endregion

    protected virtual void Dispose(bool disposing)
    {
        if (!m_disposed)
        {
            if (m_armed)
            {
                int refcnt = 0;
                do
                {
                    refcnt = System.Runtime.InteropServices.Marshal.ReleaseComObject(m_comObject);
                } while (refcnt > 0);

                m_comObject = default(T);
            }

            m_disposed = true;
        }
    }
}

---

使用（自动删除对象）
更新：添加了C#代码，并链接到Windows作业

我花了一些时间试图解决这个问题，当时XtremeVBTalk是最活跃和最有反应的。这里是我原始帖子的链接。下面是帖子的摘要，以及复制到这篇帖子的代码


使用
Application.Quit（）
和
process.Kill（）
关闭互操作进程在大部分情况下都有效，但如果应用程序发生灾难性崩溃，则会失败。例如，如果应用程序崩溃，Excel进程仍将松散运行
解决方案是让操作系统通过Win32调用处理进程的清理。当主应用程序死亡时，相关进程（如Excel）也将终止

我发现这是一个干净的解决方案，因为操作系统正在进行真正的清理工作。你所要做的就是注册Excel进程

Windows作业代码

    Excel.Application app = new Excel.ApplicationClass();
    Job job = new Job();
    uint pid = 0;
    Win32.GetWindowThreadProcessId(new IntPtr(app.Hwnd), out pid);
    job.AddProcess(Process.GetProcessById((int)pid).Handle);

包装Win32 API调用以注册互操作进程

public enum JobObjectInfoType
{
    AssociateCompletionPortInformation = 7,
    BasicLimitInformation = 2,
    BasicUIRestrictions = 4,
    EndOfJobTimeInformation = 6,
    ExtendedLimitInformation = 9,
    SecurityLimitInformation = 5,
    GroupInformation = 11
}

[StructLayout(LayoutKind.Sequential)]
public struct SECURITY_ATTRIBUTES
{
    public int nLength;
    public IntPtr lpSecurityDescriptor;
    public int bInheritHandle;
}

[StructLayout(LayoutKind.Sequential)]
struct JOBOBJECT_BASIC_LIMIT_INFORMATION
{
    public Int64 PerProcessUserTimeLimit;
    public Int64 PerJobUserTimeLimit;
    public Int16 LimitFlags;
    public UInt32 MinimumWorkingSetSize;
    public UInt32 MaximumWorkingSetSize;
    public Int16 ActiveProcessLimit;
    public Int64 Affinity;
    public Int16 PriorityClass;
    public Int16 SchedulingClass;
}

[StructLayout(LayoutKind.Sequential)]
struct IO_COUNTERS
{
    public UInt64 ReadOperationCount;
    public UInt64 WriteOperationCount;
    public UInt64 OtherOperationCount;
    public UInt64 ReadTransferCount;
    public UInt64 WriteTransferCount;
    public UInt64 OtherTransferCount;
}

[StructLayout(LayoutKind.Sequential)]
struct JOBOBJECT_EXTENDED_LIMIT_INFORMATION
{
    public JOBOBJECT_BASIC_LIMIT_INFORMATION BasicLimitInformation;
    public IO_COUNTERS IoInfo;
    public UInt32 ProcessMemoryLimit;
    public UInt32 JobMemoryLimit;
    public UInt32 PeakProcessMemoryUsed;
    public UInt32 PeakJobMemoryUsed;
}

public class Job : IDisposable
{
    [DllImport("kernel32.dll", CharSet = CharSet.Unicode)]
    static extern IntPtr CreateJobObject(object a, string lpName);

    [DllImport("kernel32.dll")]
    static extern bool SetInformationJobObject(IntPtr hJob, JobObjectInfoType infoType, IntPtr lpJobObjectInfo, uint cbJobObjectInfoLength);

    [DllImport("kernel32.dll", SetLastError = true)]
    static extern bool AssignProcessToJobObject(IntPtr job, IntPtr process);

    private IntPtr m_handle;
    private bool m_disposed = false;

    public Job()
    {
        m_handle = CreateJobObject(null, null);

        JOBOBJECT_BASIC_LIMIT_INFORMATION info = new JOBOBJECT_BASIC_LIMIT_INFORMATION();
        info.LimitFlags = 0x2000;

        JOBOBJECT_EXTENDED_LIMIT_INFORMATION extendedInfo = new JOBOBJECT_EXTENDED_LIMIT_INFORMATION();
        extendedInfo.BasicLimitInformation = info;

        int length = Marshal.SizeOf(typeof(JOBOBJECT_EXTENDED_LIMIT_INFORMATION));
        IntPtr extendedInfoPtr = Marshal.AllocHGlobal(length);
        Marshal.StructureToPtr(extendedInfo, extendedInfoPtr, false);

        if (!SetInformationJobObject(m_handle, JobObjectInfoType.ExtendedLimitInformation, extendedInfoPtr, (uint)length))
            throw new Exception(string.Format("Unable to set information.  Error: {0}", Marshal.GetLastWin32Error()));
    }

    #region IDisposable Members

    public void Dispose()
    {
        Dispose(true);
        GC.SuppressFinalize(this);
    }

    #endregion

    private void Dispose(bool disposing)
    {
        if (m_disposed)
            return;

        if (disposing) {}

        Close();
        m_disposed = true;
    }

    public void Close()
    {
        Win32.CloseHandle(m_handle);
        m_handle = IntPtr.Zero;
    }

    public bool AddProcess(IntPtr handle)
    {
        return AssignProcessToJobObject(m_handle, handle);
    }

}

关于构造函数代码的注意事项

    Excel.Application app = new Excel.ApplicationClass();
    Job job = new Job();
    uint pid = 0;
    Win32.GetWindowThreadProcessId(new IntPtr(app.Hwnd), out pid);
    job.AddProcess(Process.GetProcessById((int)pid).Handle);


在构造函数中，调用
info.LimitFlags=0x2000；
。
0x2000
是
JOB\u OBJECT\u LIMIT\u KILL\u ON\u JOB\u CLOSE
枚举值，该值定义如下：

导致与作业关联的所有进程在
作业的最后一个句柄已关闭

额外的Win32 API调用以获取进程ID（PID）

使用代码

    Excel.Application app = new Excel.ApplicationClass();
    Job job = new Job();
    uint pid = 0;
    Win32.GetWindowThreadProcessId(new IntPtr(app.Hwnd), out pid);
    job.AddProcess(Process.GetProcessById((int)pid).Handle);

普通的开发人员，你的解决方案都不适合我，
因此，我决定实施一个新的技巧

首先，让我们指定“我们的目标是什么？”=>“在任务管理器中的作业之后不查看excel对象”

 OK。让我们不要挑战并开始销毁它，但是不要破坏其他并行运行的Excel操作系统Excel。
因此，获取当前处理器的列表并获取EXCEL进程的PID，然后一旦您的工作完成，我们将在进程列表中创建一个具有唯一PID的新来宾，找到并销毁该进程
<请记住，在excel作业期间，任何新的excel进程都将被检测为新的并被销毁>
<更好的解决方案是捕获新创建的excel对象的PID并销毁它>

Process[] prs = Process.GetProcesses();
List<int> excelPID = new List<int>();
foreach (Process p in prs)
   if (p.ProcessName == "EXCEL")
       excelPID.Add(p.Id);

.... // your job 

prs = Process.GetProcesses();
foreach (Process p in prs)
   if (p.ProcessName == "EXCEL" && !excelPID.Contains(p.Id))
       p.Kill();

Process[]prs=Process.getprocesss（）；
List excelPID=新列表（）；
foreach（prs中的流程p）
如果（p.ProcessName==“EXCEL”）
添加（p.Id）；
..//你的工作
prs=Process.getprocesss（）；
foreach（prs中的流程p）
如果（p.ProcessName==“EXCEL”&&！excelPID.Contains（p.Id））
p、 杀死（）；

这就解决了我的问题，希望你的问题也能解决。
前言：我的答案包含两种解决方案，所以阅读时要小心，不要遗漏任何内容。

对于如何卸载Excel实例，有不同的方法和建议，例如：


显式释放每个com对象
与Marshal.FinalReleaseComObject（）一起使用
（不忘含蓄
已创建com对象）。要发布
每个创建的com对象，您都可以使用
这里提到的两点法则：


调用GC.Collect（）和
GC.WaitForPendingFinalizers（）使
CLR释放未使用的com对象*（实际上，它是有效的，请参阅我的第二个解决方案以了解详细信息）

正在检查com服务器应用程序
可能会显示一个等待的消息框
要回答的用户（尽管我不是
确定它可以阻止Excel
接近尾声，但我听说过几次
（次）

将WM_关闭消息发送到主服务器
Excel窗口

执行有效的函数
在单独的AppDomain中使用Excel。
有些人相信这个例子
将在AppDomain关闭时关闭
卸载

杀死所有在excel互操作代码启动后实例化的excel实例


但是！有时所有这些选项都没有帮助或不合适

例如，昨天我发现在我的一个函数（与excel一起工作）中，excel在函数结束后继续运行。我尝试了所有操作！我彻底检查了整个函数10次，并为所有操作添加了Marshal.FinalReleaseComObject（）！我还有GC.Collect（）和GC.WaitForPendingFinalizers（）。我检查了隐藏的消息框。我试图将WM_CLOSE消息发送到Excel主窗口。我在单独的AppDomain中执行了我的函数并卸载了该域。没有任何帮助！关闭所有Excel实例的选项不合适，因为如果用户启动另一个Excel
Worksheets sheets = null;
Worksheet sheet = null
try
{ 
    sheets = excelApp.Worksheets;
    sheet = sheets(1);
    ...
}
finally
{
    if (sheets != null) Marshal.ReleaseComObject(sheets);
    if (sheet != null) Marshal.ReleaseComObject(sheet);
}

// Cleanup
GC.Collect();
GC.WaitForPendingFinalizers();

Marshal.FinalReleaseComObject(xlRng);
Marshal.FinalReleaseComObject(xlSheet);

xlBook.Close(Type.Missing, Type.Missing, Type.Missing);
Marshal.FinalReleaseComObject(xlBook);

xlApp.Quit();
Marshal.FinalReleaseComObject(xlApp);

GC.Collect();
GC.WaitForPendingFinalizers();
GC.Collect();
GC.WaitForPendingFinalizers();

    CultureInfo en_US = new System.Globalization.CultureInfo("en-US"); 
    System.Threading.Thread.CurrentThread.CurrentCulture = en_US;
    string filePathLocal = _applicationObject.ActiveWorkbook.Path;
    System.Threading.Thread.CurrentThread.CurrentCulture = orgCulture;

using (AutoReleaseComObject<Application> excelApplicationWrapper = new AutoReleaseComObject<Application>(new Application()))
{
    try
    {
        using (AutoReleaseComObject<Workbook> workbookWrapper = new AutoReleaseComObject<Workbook>(excelApplicationWrapper.ComObject.Workbooks.Open(namedRangeBase.FullName, false, false, missing, missing, missing, true, missing, missing, true, missing, missing, missing, missing, missing)))
        {
           // do something with your workbook....
        }
    }
    finally
    {
         excelApplicationWrapper.ComObject.Quit();
    } 
}

public class AutoReleaseComObject<T> : IDisposable
{
    private T m_comObject;
    private bool m_armed = true;
    private bool m_disposed = false;

    public AutoReleaseComObject(T comObject)
    {
        Debug.Assert(comObject != null);
        m_comObject = comObject;
    }

#if DEBUG
    ~AutoReleaseComObject()
    {
        // We should have been disposed using Dispose().
        Debug.WriteLine("Finalize being called, should have been disposed");

        if (this.ComObject != null)
        {
            Debug.WriteLine(string.Format("ComObject was not null:{0}, name:{1}.", this.ComObject, this.ComObjectName));
        }

        //Debug.Assert(false);
    }
#endif

    public T ComObject
    {
        get
        {
            Debug.Assert(!m_disposed);
            return m_comObject;
        }
    }

    private string ComObjectName
    {
        get
        {
            if(this.ComObject is Microsoft.Office.Interop.Excel.Workbook)
            {
                return ((Microsoft.Office.Interop.Excel.Workbook)this.ComObject).Name;
            }

            return null;
        }
    }

    public void Disarm()
    {
        Debug.Assert(!m_disposed);
        m_armed = false;
    }

    #region IDisposable Members

    public void Dispose()
    {
        Dispose(true);
#if DEBUG
        GC.SuppressFinalize(this);
#endif
    }

    #endregion

    protected virtual void Dispose(bool disposing)
    {
        if (!m_disposed)
        {
            if (m_armed)
            {
                int refcnt = 0;
                do
                {
                    refcnt = System.Runtime.InteropServices.Marshal.ReleaseComObject(m_comObject);
                } while (refcnt > 0);

                m_comObject = default(T);
            }

            m_disposed = true;
        }
    }
}

public enum JobObjectInfoType
{
    AssociateCompletionPortInformation = 7,
    BasicLimitInformation = 2,
    BasicUIRestrictions = 4,
    EndOfJobTimeInformation = 6,
    ExtendedLimitInformation = 9,
    SecurityLimitInformation = 5,
    GroupInformation = 11
}

[StructLayout(LayoutKind.Sequential)]
public struct SECURITY_ATTRIBUTES
{
    public int nLength;
    public IntPtr lpSecurityDescriptor;
    public int bInheritHandle;
}

[StructLayout(LayoutKind.Sequential)]
struct JOBOBJECT_BASIC_LIMIT_INFORMATION
{
    public Int64 PerProcessUserTimeLimit;
    public Int64 PerJobUserTimeLimit;
    public Int16 LimitFlags;
    public UInt32 MinimumWorkingSetSize;
    public UInt32 MaximumWorkingSetSize;
    public Int16 ActiveProcessLimit;
    public Int64 Affinity;
    public Int16 PriorityClass;
    public Int16 SchedulingClass;
}

[StructLayout(LayoutKind.Sequential)]
struct IO_COUNTERS
{
    public UInt64 ReadOperationCount;
    public UInt64 WriteOperationCount;
    public UInt64 OtherOperationCount;
    public UInt64 ReadTransferCount;
    public UInt64 WriteTransferCount;
    public UInt64 OtherTransferCount;
}

[StructLayout(LayoutKind.Sequential)]
struct JOBOBJECT_EXTENDED_LIMIT_INFORMATION
{
    public JOBOBJECT_BASIC_LIMIT_INFORMATION BasicLimitInformation;
    public IO_COUNTERS IoInfo;
    public UInt32 ProcessMemoryLimit;
    public UInt32 JobMemoryLimit;
    public UInt32 PeakProcessMemoryUsed;
    public UInt32 PeakJobMemoryUsed;
}

public class Job : IDisposable
{
    [DllImport("kernel32.dll", CharSet = CharSet.Unicode)]
    static extern IntPtr CreateJobObject(object a, string lpName);

    [DllImport("kernel32.dll")]
    static extern bool SetInformationJobObject(IntPtr hJob, JobObjectInfoType infoType, IntPtr lpJobObjectInfo, uint cbJobObjectInfoLength);

    [DllImport("kernel32.dll", SetLastError = true)]
    static extern bool AssignProcessToJobObject(IntPtr job, IntPtr process);

    private IntPtr m_handle;
    private bool m_disposed = false;

    public Job()
    {
        m_handle = CreateJobObject(null, null);

        JOBOBJECT_BASIC_LIMIT_INFORMATION info = new JOBOBJECT_BASIC_LIMIT_INFORMATION();
        info.LimitFlags = 0x2000;

        JOBOBJECT_EXTENDED_LIMIT_INFORMATION extendedInfo = new JOBOBJECT_EXTENDED_LIMIT_INFORMATION();
        extendedInfo.BasicLimitInformation = info;

        int length = Marshal.SizeOf(typeof(JOBOBJECT_EXTENDED_LIMIT_INFORMATION));
        IntPtr extendedInfoPtr = Marshal.AllocHGlobal(length);
        Marshal.StructureToPtr(extendedInfo, extendedInfoPtr, false);

        if (!SetInformationJobObject(m_handle, JobObjectInfoType.ExtendedLimitInformation, extendedInfoPtr, (uint)length))
            throw new Exception(string.Format("Unable to set information.  Error: {0}", Marshal.GetLastWin32Error()));
    }

    #region IDisposable Members

    public void Dispose()
    {
        Dispose(true);
        GC.SuppressFinalize(this);
    }

    #endregion

    private void Dispose(bool disposing)
    {
        if (m_disposed)
            return;

        if (disposing) {}

        Close();
        m_disposed = true;
    }

    public void Close()
    {
        Win32.CloseHandle(m_handle);
        m_handle = IntPtr.Zero;
    }

    public bool AddProcess(IntPtr handle)
    {
        return AssignProcessToJobObject(m_handle, handle);
    }

}

    [DllImport("user32.dll", SetLastError = true)]
    public static extern uint GetWindowThreadProcessId(IntPtr hWnd, out uint lpdwProcessId);

    Excel.Application app = new Excel.ApplicationClass();
    Job job = new Job();
    uint pid = 0;
    Win32.GetWindowThreadProcessId(new IntPtr(app.Hwnd), out pid);
    job.AddProcess(Process.GetProcessById((int)pid).Handle);

Process[] prs = Process.GetProcesses();
List<int> excelPID = new List<int>();
foreach (Process p in prs)
   if (p.ProcessName == "EXCEL")
       excelPID.Add(p.Id);

.... // your job 

prs = Process.GetProcesses();
foreach (Process p in prs)
   if (p.ProcessName == "EXCEL" && !excelPID.Contains(p.Id))
       p.Kill();

[DllImport("user32.dll")]
private static extern uint GetWindowThreadProcessId(IntPtr hWnd, out uint lpdwProcessId);

/// <summary> Tries to find and kill process by hWnd to the main window of the process.</summary>
/// <param name="hWnd">Handle to the main window of the process.</param>
/// <returns>True if process was found and killed. False if process was not found by hWnd or if it could not be killed.</returns>
public static bool TryKillProcessByMainWindowHwnd(int hWnd)
{
    uint processID;
    GetWindowThreadProcessId((IntPtr)hWnd, out processID);
    if(processID == 0) return false;
    try
    {
        Process.GetProcessById((int)processID).Kill();
    }
    catch (ArgumentException)
    {
        return false;
    }
    catch (Win32Exception)
    {
        return false;
    }
    catch (NotSupportedException)
    {
        return false;
    }
    catch (InvalidOperationException)
    {
        return false;
    }
    return true;
}

/// <summary> Finds and kills process by hWnd to the main window of the process.</summary>
/// <param name="hWnd">Handle to the main window of the process.</param>
/// <exception cref="ArgumentException">
/// Thrown when process is not found by the hWnd parameter (the process is not running). 
/// The identifier of the process might be expired.
/// </exception>
/// <exception cref="Win32Exception">See Process.Kill() exceptions documentation.</exception>
/// <exception cref="NotSupportedException">See Process.Kill() exceptions documentation.</exception>
/// <exception cref="InvalidOperationException">See Process.Kill() exceptions documentation.</exception>
public static void KillProcessByMainWindowHwnd(int hWnd)
{
    uint processID;
    GetWindowThreadProcessId((IntPtr)hWnd, out processID);
    if (processID == 0)
        throw new ArgumentException("Process has not been found by the given main window handle.", "hWnd");
    Process.GetProcessById((int)processID).Kill();
}

int hWnd = xl.Application.Hwnd;
// ...
// here we try to close Excel as usual, with xl.Quit(),
// Marshal.FinalReleaseComObject(xl) and so on
// ...
TryKillProcessByMainWindowHwnd(hWnd);

void GenerateWorkbook(...)
{
  ApplicationClass xl;
  Workbook xlWB;
  try
  {
    xl = ...
    xlWB = xl.Workbooks.Add(...);
    ...
  }
  finally
  {
    ...
    Marshal.ReleaseComObject(xlWB)
    ...
    GC.Collect();
    GC.WaitForPendingFinalizers();
  }
}

void GenerateWorkbook(...)
{
  try
  {
    GenerateWorkbookInternal(...);
  }
  finally
  {
    GC.Collect();
    GC.WaitForPendingFinalizers();
  }
}

private void GenerateWorkbookInternal(...)
{
  ApplicationClass xl;
  Workbook xlWB;
  try
  {
    xl = ...
    xlWB = xl.Workbooks.Add(...);
    ...
  }
  finally
  {
    ...
    Marshal.ReleaseComObject(xlWB)
    ...
  }
}

public Excel.Style xlStyleHeader = null;

private void CreateHeaderStyle()
{
    Excel.Styles xlStyles = null;
    Excel.Font xlFont = null;
    Excel.Interior xlInterior = null;
    Excel.Borders xlBorders = null;
    Excel.Border xlBorderBottom = null;

    try
    {
        xlStyles = xlWorkbook.Styles;
        xlStyleHeader = xlStyles.Add("Header", Type.Missing);

        // Text Format
        xlStyleHeader.NumberFormat = "@";

        // Bold
        xlFont = xlStyleHeader.Font;
        xlFont.Bold = true;

        // Light Gray Cell Color
        xlInterior = xlStyleHeader.Interior;
        xlInterior.Color = 12632256;

        // Medium Bottom border
        xlBorders = xlStyleHeader.Borders;
        xlBorderBottom = xlBorders[Excel.XlBordersIndex.xlEdgeBottom];
        xlBorderBottom.Weight = Excel.XlBorderWeight.xlMedium;
    }
    catch (Exception ex)
    {
        throw ex;
    }
    finally
    {
        Release(xlBorderBottom);
        Release(xlBorders);
        Release(xlInterior);
        Release(xlFont);
        Release(xlStyles);
    }
}

private void Release(object obj)
{
    // Errors are ignored per Microsoft's suggestion for this type of function:
    // http://support.microsoft.com/default.aspx/kb/317109
    try
    {
        System.Runtime.InteropServices.Marshal.ReleaseComObject(obj);
    }
    catch { } 
}

objExcel = new Excel.Application();  
objBook = (Excel.Workbook)(objExcel.Workbooks.Add(Type.Missing)); 

objBook.Close(true, Type.Missing, Type.Missing); 
objExcel.Application.Quit();
objExcel.Quit(); 

For Each objWorkBook As WorkBook in objWorkBooks 'local ref, created from ExcelApp.WorkBooks to avoid the double-dot
   objWorkBook.Close 'or whatever
   FinalReleaseComObject(objWorkBook)
   objWorkBook = Nothing
Next 

'The above does not work, and this is the workaround:

For intCounter As Integer = 1 To mobjExcel_WorkBooks.Count
   Dim objTempWorkBook As Workbook = mobjExcel_WorkBooks.Item(intCounter)
   objTempWorkBook.Saved = True
   objTempWorkBook.Close(False, Type.Missing, Type.Missing)
   FinalReleaseComObject(objTempWorkBook)
   objTempWorkBook = Nothing
Next

app.workbooks.Close();
Thread.Sleep(500); // adjust, for me it works at around 300+
app.Quit();

...
FinalReleaseComObject(app);

if (!mDisposed) {
   mExcel = null;
   GC.Collect();
   mDisposed = true;
}

Excel.Range rng = (Excel.Range)worksheet.Cells[1, 1];
worksheet.Paste(rng, false);
releaseObject(rng);

public class Test {

    // These instance variables must be nulled or Excel will not quit
    private Excel.Application xl;
    private Excel.Workbook book;

    public void DoSomething()
    {
        xl = new Excel.Application();
        xl.Visible = true;
        book = xl.Workbooks.Add(Type.Missing);

        // These variables are locally scoped, so we need not worry about them.
        // Notice I don't care about using two dots.
        Excel.Range rng = book.Worksheets[1].UsedRange;
    }

    public void CleanUp()
    {
        book = null;
        xl.Quit();
        xl = null;

        GC.Collect();
        GC.WaitForPendingFinalizers();
        GC.Collect();
        GC.WaitForPendingFinalizers();
    }
}

public class MyExcelInteropClass
{
    Excel.Application xlApp;
    Excel.Workbook xlBook;

    public void dothingswithExcel() 
    {
        try { /* Do stuff manipulating cells sheets and workbooks ... */ }
        catch {}
        finally {KillExcelProcess(xlApp);}
    }

    static void KillExcelProcess(Excel.Application xlApp)
    {
        if (xlApp != null)
        {
            int excelProcessId = 0;
            GetWindowThreadProcessId(xlApp.Hwnd, out excelProcessId);
            Process p = Process.GetProcessById(excelProcessId);
            p.Kill();
            xlApp = null;
        }
    }

    [DllImport("user32.dll")]
    static extern int GetWindowThreadProcessId(int hWnd, out int lpdwProcessId);
}

GC.Collect();
GC.WaitForPendingFinalizers();

private void FunctionWrapper(string sourcePath, string targetPath)
{
    try
    {
        FunctionThatCallsExcel(sourcePath, targetPath);
    }
    finally
    {
        GC.Collect();
        GC.WaitForPendingFinalizers();
    }
}

private static void Clean()
{
    workBook.Close();
    Marshall.ReleaseComObject(workBook);
    excel.Quit();
    CG.Collect();
    CG.WaitForPendingFinalizers();
}

excel = new Microsoft.Office.Interop.Excel.Application();
var process = Process.GetProcessesByName("EXCEL").OrderByDescending(p => p.StartTime).First();

if (!process.HasExited)
   process.Kill();

[DllImport("user32.dll")]
static extern int GetWindowThreadProcessId(int hWnd, out int lpdwProcessId);

private void GenerateExcel()
{
    var excel = new Microsoft.Office.Interop.Excel.Application();
    int id;
    // Find the Excel Process Id (ath the end, you kill him
    GetWindowThreadProcessId(excel.Hwnd, out id);
    Process excelProcess = Process.GetProcessById(id);

try
{
    // Your code
}
finally
{
    excel.Quit();

    // Kill him !
    excelProcess.Kill();
}

if (xlApp != null)
{
    xlApp.Workbooks.Close();
    xlApp.Quit();
}

System.Diagnostics.Process[] processArray = System.Diagnostics.Process.GetProcessesByName("EXCEL");
foreach (System.Diagnostics.Process process in processArray)
{
    if (process.MainWindowTitle.Length == 0) { process.Kill(); }
}

Sub WrapperThatCleansUp()

    ' NOTE: Don't call Excel objects in here... 
    '       Debugger would keep alive until end, preventing GC cleanup

    ' Call a separate function that talks to Excel
    DoTheWork()

    ' Now let the GC clean up (twice, to clean up cycles too)
    GC.Collect()    
    GC.WaitForPendingFinalizers()
    GC.Collect()    
    GC.WaitForPendingFinalizers()

End Sub

Sub DoTheWork()
    Dim app As New Microsoft.Office.Interop.Excel.Application
    Dim book As Microsoft.Office.Interop.Excel.Workbook = app.Workbooks.Add()
    Dim worksheet As Microsoft.Office.Interop.Excel.Worksheet = book.Worksheets("Sheet1")
    app.Visible = True
    For i As Integer = 1 To 10
        worksheet.Cells.Range("A" & i).Value = "Hello"
    Next
    book.Save()
    book.Close()
    app.Quit()

    ' NOTE: No calls the Marshal.ReleaseComObject() are ever needed
End Sub

public static void SweepExcelProcesses()
{           
            if (Process.GetProcessesByName("EXCEL").Length != 0)
            {
                Process[] processes = Process.GetProcesses();
                foreach (Process process in processes)
                {
                    if (process.ProcessName.ToString() == "excel")
                    {                           
                        string title = process.MainWindowTitle;
                    }
                }
            }
}