Xamarin 无法实例化应用程序mono.android.app.application…没有'；“找不到类”；mono.android.app.Application“；

我的项目启用Muti Dec选项，只要引用xamarin绑定库Vitamio，我的应用程序启动就会崩溃！错误信息如下：

Forwarding debugger port 8824
    Detecting existing process
    [AndroidRuntime] Shutting down VM
    [AndroidRuntime] FATAL EXCEPTION: main
    [AndroidRuntime] Process: AnXinMe.RemoteTv.Droid, PID: 21244
    [AndroidRuntime] java.lang.RuntimeException: Unable to instantiate application mono.android.app.Application: java.lang.ClassNotFoundException: Didn't find class "mono.android.app.Application" on path: DexPathList[[zip file "/data/app/AnXinMe.RemoteTv.Droid-1.apk"],nativeLibraryDirectories=[/data/app-lib/AnXinMe.RemoteTv.Droid-1, /vendor/lib, /system/lib]]
    [AndroidRuntime]    at android.app.LoadedApk.makeApplication(LoadedApk.java:509)
    [AndroidRuntime]    at android.app.ActivityThread.handleBindApplication(ActivityThread.java:4427)
    [AndroidRuntime]    at android.app.ActivityThread.access$1500(ActivityThread.java:147)
    [AndroidRuntime]    at android.app.ActivityThread$H.handleMessage(ActivityThread.java:1271)
    [AndroidRuntime]    at android.os.Handler.dispatchMessage(Handler.java:102)
    [AndroidRuntime]    at android.os.Looper.loop(Looper.java:136)
    [AndroidRuntime]    at android.app.ActivityThread.main(ActivityThread.java:5135)
    [AndroidRuntime]    at java.lang.reflect.Method.invokeNative(Native Method)
    [AndroidRuntime]    at java.lang.reflect.Method.invoke(Method.java:515)
    [AndroidRuntime]    at com.android.internal.os.ZygoteInit$MethodAndArgsCaller.run(ZygoteInit.java:795)
    [AndroidRuntime]    at com.android.internal.os.ZygoteInit.main(ZygoteInit.java:611)
    [AndroidRuntime]    at dalvik.system.NativeStart.main(Native Method)
    [AndroidRuntime] Caused by: java.lang.ClassNotFoundException: Didn't find class "mono.android.app.Application" on path: DexPathList[[zip file "/data/app/AnXinMe.RemoteTv.Droid-1.apk"],nativeLibraryDirectories=[/data/app-lib/AnXinMe.RemoteTv.Droid-1, /vendor/lib, /system/lib]]
    [AndroidRuntime]    at dalvik.system.BaseDexClassLoader.findClass(BaseDexClassLoader.java:56)
    [AndroidRuntime]    at java.lang.ClassLoader.loadClass(ClassLoader.java:497)
    [AndroidRuntime]    at java.lang.ClassLoader.loadClass(ClassLoader.java:457)
    [AndroidRuntime]    at android.app.Instrumentation.newApplication(Instrumentation.java:975)
    [AndroidRuntime]    at android.app.LoadedApk.makeApplication(LoadedApk.java:504)
    [AndroidRuntime]    ... 11 more
    [Process] Sending signal. PID: 21244 SIG: 9

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是xamarin病毒吗？请帮帮我！谢谢

你使用的是什么版本的Xamarin.Android？Xamarin.VisualStudio_4.0.1.147您可以通过Sushingover提到的方法解决此问题。如果不需要使用Multi-dex，可以尝试删除一些不用于达到65k方法限制的大型lib。否则，您需要应用注释5和注释10中的此修复：