如何在R中将字符转换为二进制值

我有一个带有*和-的数据帧，我想把*转换成1，把-转换成0，但我不知道该怎么做

这是我的数据帧

> head(Patient_036)
       Driver SNV_Organoid_036 INDEL_Organoid_036 Deletion_Organoid_036
ABCB1       *                -                  *                     -
ACVR1B      *                *                  *                     -
ACVR2A      *                *                  -                     -
APC         *                -                  *                     -
ARID1A      *                -                  *                     -
ARID1B      *                *                  -                     -

有什么帮助吗？

Patient_036[Patient_036==“*”]很抱歉，我得到了所有的NA:（我的数据太大了，我无法计算有多少*和-因为它们随机分布在我的数据框中。
Patient_036[Patient_036 == "*"] <- 1
Patient_036[Patient_036 == "-"] <- 0

Patient_036 <- structure(list(Driver = c("1", "1", "1", "1", "1", "1"), SNV_Organoid_036 = c("0", 
"1", "1", "0", "0", "1"), INDEL_Organoid_036 = c("1", "1", "0", 
"1", "1", "0"), Deletion_Organoid_036 = c("0", "0", "0", "0", 
"0", "0")), row.names = c("ABCB1", "ACVR1B", "ACVR2A", "APC", 
"ARID1A", "ARID1B"), class = "data.frame")