如何在Python pyqt4 GUI设计中使用线程

我已经编写了一个简单的PythonGUI代码，用于将代码休眠10秒钟。同时，GUI应该在不冻结的情况下运行。定义primari thready和secondary thread不可能吗？当我点击“运行”按钮时，pythonw.exe已经停止工作。有人对我如何解决这个问题有什么想法吗？多谢各位

    import sys, threading
    from PyQt4 import QtGui, QtCore
    from PyQt4.QtCore import pyqtSlot
    from PyQt4.QtGui import *

    class Window(QtGui.QMainWindow):
        def __init__(self):
            super(Window,self).__init__()
            self.setGeometry(400,150, 550, 500)
            self.setWindowTitle("my first program")
            self.home()

        def home(self):
            self.button_1 = QtGui.QPushButton('Run', self)
            self.button_1.resize(60,25)
            self.button_1.move(230,230)
            self.button_1.clicked.connect(self.Thread_test)

            self.textbox_1 = QTextEdit(self)
            self.textbox_1.move(15,290)
            self.textbox_1.resize(510,170)

            self.show()

        def Thread_test(self):
            t = threading.Thread(target=self.calculation)
            t.start()

        def calculation(self):
            msg="program is working"
            self.textbox_1.setText(msg)
            time.sleep(5)
            msg="program was slept for few sec."
            self.textbox_1.setText(msg)

    def run():
        app=QtGui.QApplication(sys.argv)
        GUI=Window()
        sys.exit(app.exec_())    
    run()

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Qt小部件不是线程安全的。您应该仅从创建小部件的线程访问它。见：

所有小部件和几个相关类[…]都不能在辅助线程中工作

您必须通知主（GUI）线程以更新UI。您可以使用信号和插槽执行此操作