Asp.net web api 什么可能导致OWIN间歇性无法加载？

最近，我们的开发服务器上开始出现一些不寻常的错误。我们正在使用Jenkins构建和部署一个ASP.NET Web API，该API使用OWIN，到目前为止，一切都正常工作。但是，最近我们开始间歇性地看到错误，如以下从Windows事件日志中轻微编辑的错误：

Exception information: 
    Exception type: EntryPointNotFoundException 
    Exception message: The following errors occurred while attempting to load the app.
 - No assembly found containing an OwinStartupAttribute.
 - The given type or method 'Api.Startup' was not found. Try specifying the Assembly.
To disable OWIN startup discovery, add the appSetting owin:AutomaticAppStartup with a value of "false" in your web.config.
To specify the OWIN startup Assembly, Class, or Method, add the appSetting owin:AppStartup with the fully qualified startup class or configuration method name in your web.config.
   at Microsoft.Owin.Host.SystemWeb.OwinBuilder.GetAppStartup()
   at Microsoft.Owin.Host.SystemWeb.OwinHttpModule.InitializeBlueprint()
   at System.Threading.LazyInitializer.EnsureInitializedCore[T](T& target, Boolean& initialized, Object& syncLock, Func`1 valueFactory)
   at Microsoft.Owin.Host.SystemWeb.OwinHttpModule.Init(HttpApplication context)
   at System.Web.HttpApplication.RegisterEventSubscriptionsWithIIS(IntPtr appContext, HttpContext context, MethodInfo[] handlers)
   at System.Web.HttpApplication.InitSpecial(HttpApplicationState state, MethodInfo[] handlers, IntPtr appContext, HttpContext context)
   at System.Web.HttpApplicationFactory.GetSpecialApplicationInstance(IntPtr appContext, HttpContext context)
   at System.Web.Hosting.PipelineRuntime.InitializeApplication(IntPtr appContext)

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回收IIS应用程序池通常可以解决此问题，但实际情况令人担忧。你知道是什么导致了这种情况吗？

你的创业课程是什么样子的？它是否具有

OwinStartup

属性？您的Web.config的appSettings中有任何

owin:

键吗？@CrazyPyro感谢您的回复，但请注意时间戳。这是近一年前的一个问题，因此在这段时间内，对源代码的访问已经丢失。